I used to be a moderate drinker, having 1-2 per day several times a week. After stopping completely about 8 or 9 months ago, I no longer have acid reflux or that burning feeling in the back of my throat from spicy food.
This was an unexpected and wonderful result, to say nothing of dramatic weight loss and other benefits.
I used to think there could be health benefits to moderate drinking, but in retrospect it was only a justification for unhealthy behavior.
An altered immune response makes sense, given what alcohol puts your body through.