No. Especially on a non-mobile screen. I used to have better-than 20/20 vision, I would guess that I now have around 20/20 vision. I find the text to be too small on the home page and scrunched up. I'm on a 4k monitor, and the front page stops at "30" and wants me to click "More" instead of loading in more posts automatically (and loading in even more as I scroll). I find this inconvenient and wasteful - I'd much rather each post take up more height, and I'd strongly prefer a "infinite" scrolling system. Even if I was on a 1080p monitor, I'd rather have each post on the front page take up double the amount of vertical space it does now than have it's current UI. The loss of information density would be (to me) well worth it.

I've switched from a mac and iPhone to Linux and Android, and as you can tell, I'm still on HN. Clearly, design isn't absolutely everything to me. But the notion that aesthetics "get in the way for the most part" is one I and most other developers I know in real life disagree with. I'd argue that HN's aesthetics get in the way. I personally have used browser extensions to change the HN CSS, due to how much I dislike the UI.