One thing I see regularly is Chrome’s web caching being so aggressive it is driving front-end developers to start using FF for dev.
We simply need to stand back and let time take its course.
Issue 645845 (Open, ~4 years old): DevTools: "disable cache" doesn't work for media resources: https://bugs.chromium.org/p/chromium/issues/detail?id=645845
Issue 470030 (WontFix): 'Disable cache' should prevent HSTS redirects: https://bugs.chromium.org/p/chromium/issues/detail?id=574345
Issue 775435 (Fixed after ~1 year): Disable cache does not disable cached redirects https://bugs.chromium.org/p/chromium/issues/detail?id=775435
The other thing that I should have mentioned is with non-dev staff. When new builds and updates get pushed out, they often have problems because of Chrome's aggressive caching. This group isn't as privy to knowing about developer tools and chaching, and it is highly frustrating and annoying for them. It seems like they will still use Chrome for casual browsing, but then start to use Firefox or Safari for testing builds.
I use Firefox 100% of the time and very very rarely have these kinds of issues.
All I can say is that something is seriously wrong with Chrome's caching policy, from a UX perspective. People do get frustrated in ways that they don't when using Safari or Firefox.
Alternatively if you just hate caching you can set cache control headers on your js.
I think tying caching behavior to Google's web sites is silly, caching is a crucial part of performance for any heavy web application.
Every other browser seems to find a sane middle ground.
Anyway this was never about my own practices, this was about how Chrome has become annoying and how it will result in attrition. The faster this happens, the better.