When I was in grad school I was a TA for a biochemistry class and the prof asked me to deliver the lecture on crystallography while he was on vaca. Part of the lecture was about how electron microscopy was easier but pretty inaccurate compared to x-ray crystallography. But the slides were 10 years out of date, the accuracy of EM was still not as good but the gap was much smaller. So I updated them with more recent EM results from the same labs.

When the prof came back he spent the first 5m of the next lecture "correcting" me, explaining that EM sucked, x-ray was the only good technique. I realized that he had basically made up his mind decades earlier and no matter what changed in the technology he wasn't going to change his opinion. Science has its own politics, similar to actual politics in that conclusions drive observations, but instead of being about minimum wage or housing supply it's about arcane scientific techniques.