Grapefruit juice combined with Vitamin D drops caused me a lasting headache, which, in hindsight, was like a sinus infection without the sinus infection part, but including the typically incredibly stiff neck.
Lasting here means a whole month. One month of continuous headache. Not headaches. One gigantic headache. Mostly 7/10, two times 9/10, at which points we called the ambulance because I couldn't take it anymore.
Don't ever mix grapefruit juice with anything.