I don't consider myself a FIRE enthusiast, but one thing I've noticed is that people who work a lot often don't "have time" to pay attention to their health. Once you hit about 40, I see a very sharp divergence in health outcomes.
In other words, some 40 year olds are indistinguishable from 30 year olds. Others have all sorts of minor chronic issues that pile up and lead to a miserable second half of life. Health and disease are "nonlinear" -- a health problem often snowballs into others.
Sleep seems to be a big one. Most people sleep poorly and don't know why. This leads to problems all the way up the chain, like heart issues and dental problems.
Diet is obviously another foundational issue. It's hard to eat well in many parts of America if you don't cook. Ordering from a restaurant every day is a way to eat too much salt, sugar, and fat. And yes I realize that lots of people are rolling their eyes at that.
It sounds like a minor issue until you compound it over 20 years. In other words, it's something you don't really care about in your 20's and 30's. But it catches up, and I recall reading a thread about "being old" on HN where lots of people mainly regret and are scared of health issues.
Exercise takes time too. I exercised 5+ days a week when working, but now I do it even more, and it's worth it.
You can obviously pay attention to your health and work at the same time, but I find that many people don't (e.g. in San Francisco).
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edit, found the thread: https://news.ycombinator.com/item?id=24527978