https://en.wikipedia.org/wiki/Time_of_useful_consciousness
Most commercial flights are operating in the 30,000-39,000 range.
FlightSafety International's training materials indicate that TUC could be cut in half if the decompression is explosive.
But, for sake of argument, it assumes a few things:
1) That your lungs are healthy enough to hold your breath for >= 1 minute (not all are)
2) You actually have the opportunity to breath in a lungful of oxygen-rich air (depending on the situation/timing, this might not be the case)
3) You have your wits about you while a very stressful situation unfolds around you (let's argue that you, personally, are cool and collected under pressure - this; however, is not universally true for all other passengers)
So not only are you unable to get more oxygen, your lungs are actively sucking the remaining oxygen out of your blood.
Edit: as was pointed out in this comment a level up on this thread https://news.ycombinator.com/item?id=24495970
With a sudden event, you’d have about 15 seconds because there’s a lot to panic about.
Edit: just tried. 25s panic started, 30s my chest was trying to inhale, 36s I had to let myself breathe. This was at my desk while calm and in control.
On a plane I’d probably panic sooner and might be able to go a full minute before actually passing out.
Edit 2: I did use to freedive as a kid and am in very good shape (45 resting heart rate) so maybe that helps
On the subject at hand, the best freediver in the planet would still have zero chance in a low pressure environment.
Also, at 1ATM you have 14.7 lb/square inch in your lungs, at 30,000 feet that drops to 4.3 psi making trying to hold your breath dangerous on it’s own.
It is a huge gamble that you would or could hold your breath at the opportune moment.
With a lack of oxygen in the air, you will quickly and painlessly blackout and then die.
https://expertaviator.com/wp-content/uploads/2012/04/TimeOfU...