This is pretty much a parsely ad. I think the HN crowd is pretty aware that ad blockers, vpns, etc can break analytics.
I suppose if nothing else it's good to know so you can immediately beef up your numbers +20% in your slide deck for VCs.
What if you're trying to get stats about people who don't convert or otherwise give you a signal that they're using the site?
I've run into sites where things like signup or checkout are blocked behind an analytics tracker (Adobe used to recommend running theirs in a synchronous navigation-blocking mode) which meant that any problem with that service was completely invisible unless they contacted you to complain.
I also remember people wondering why Firefox users stopped using their site when they shipped the release which enabled tracking protection by default.