Simplifying it down to "multiplying wealth by 10,000x" is naive.
It's a lot easier to turn $10M into $100B than it is to turn $100 into $1M.
With $10M, you already have the basics handled. You can have a house and car that are paid off and enough cash stashed away to handle living expenses for the rest of your life and still have $7M+ to piss away. If you're smart and never dip into the funds reserved for lifetime living expenses, it's impossible to fail.
With only $100, you're struggling to put food on the table. Possibly even working two jobs with no time to work on building a business.
And here, I haven't even touched on the concept of "connections". Someone with an 8-figure bank account likely knows who to talk to when it comes to getting a product in front of the right people.
If Bill's parents had only $100 and turned it into $1M, then definitely, he'd be self-made. But since he started with likely an 8-figure backing, he's definitely not.