Government force in what way? There's a big difference between telling typhoid mary that she can't work as a cook any more and telling everyone he must risk his job and livelihood for a small number of at-risk people.
A quick Googling suggests about 60 million people over 65 in the US. Then we should add some millions for problems like diabetes. So, 1 in 5? 1 in 4?
Further, some young people seem to have permanent lung damage from the disease.
I'm saying the principle is clear.