The only trouble I ever had with my Atari ST mouse, which I used for about 10 years, was that the axles got dusty. Well, dusty is an understatement. It was a mechanical mouse, with two axles and a ball with a plastic coating of some kind. As you moved the mouse, the ball brought the axles into motion, thus tracking your (more or less) exact movements.

Every few months I had to use my Swiss knife to scrape the accumulated dirt and dust from the axles. With some finesse, so as not to damage the axles.

The mouse could take quite some abuse too. I used to play Arkanoid (also known as Breakout) a lot, at some point. As well as other games which required a lot of clicking and moving around.