it likely started with apple killing firewire (which immediately ended numerous product lines and EOL'ed many people's devices).
it continued with the redesign of final cut, which was clearly done to appeal to new(ish) users rather than people who used it all day.
the arrival of AUv3 has been somewhat half-assed, with poor documentation and inconsistent experiences among developers. developers using higher level audio APIs have also found things changing with no clear reason or announcements.
the mac hardware has continued to become less and less competitively priced if you care about CPU cycles/unit-of-currency.
the demise of connectors on macbooks was hard on many musicians who were performing live with their machines.
continued subtle OS-level changes continue to break many pro-audio/music creation apps in not necessarily deep ways, but the breakages still have to be addressed by someone.
there have been repeated reports of significant worsening of performance of various types of audio interfaces as macOS has moved from version to version. i tended to dimiss these initially, but they are becoming too common to completely write off. the machines are becoming more and more sensitive to the entire state of the USB bus(ses), and although they were never entirely safe in this respect, things have gotten worse just as USB connectivity for audio has become more and more important.
that's a sampling ...
https://appleinsider.com/articles/19/02/19/pro-audio-glitch-...