I'm sorry, what?
I use them all the time. F5 for refreshing all kinds of stuff, or for setting breakpoints in my IDE. F7, F8, F9 for controlling the debugger, other combinations for building/running. F12 for opening developer tools in the browser. Some programs still use F1 for help. F2 in Windows explorer for renaming things. And so on and so forth.
I can't stand keyboards without function keys, or where you have to press Fn to activate them.