I thought the primary appeal of HTTP/3 is for mobile clients, and bad connections in general, because it circumvents TCP head of line blocking and connections can persist across networks.
That doesn't feel terribly relevant in corporate networks.
(not disputing that it's not comparable to the v6 transition)
Enterprises largely won't give two shits about HTTP/3.
Just last week I took ownership of another department's decade old app written in VB.NET WinForms. The former dev team was putting the finishing touches on the C# WebForms refactor. It's been interesting taking a step back in time to Dev practices from 2008.
Increasingly "corporations" out-source this problem to specialists who are only too pleased to use newer technologies with better performance and collect the same money.
The application servers running the site do not accept HTTP/2 and most likely can't support it at all (we're a python shop and none of the web frameworks we use could do HTTP/2 when we looked into it).
But for companies like CloudFlare or Googl HTTP/2 means less traffic overhead (multiplexing+header compression) and can save them a lot of bandwidth (aka. money) with that.
More availability of HTTP version gateways in load balancers and other reverse proxies is all that's needed, and that's coming along.
As a motivational example, it is possible to encode a colon in a header name in http2 but not in http1.1, and this does not violate the RFC which only blacklists "\0\r\n".