I guess what gets me is that there is a hidden premise in scientific materialism that _nothing_ is alive and _nothing_ is connected, because it starts with inanimate fundamental parts and tries to build up to reality.
From a psychedelic perspective, that's backwards - if you start, instead, from "what are my perceptions" and try to extrapolate out, you start to find that the default assumptions assume there's a boundary somewhere - "light hits my retina so I see it" "my optic nerve sends a signal so I see it" "certain neurons fire so I see it" but there's no firm place to draw the line "this is where the light stops and where the perception begins", your body and the light are one machine, going from the big bang through the star through space through objects through your eye through your brain - there's no solid boundary between any of those things, it's one long unbroken string of causality.
Or, you're having a conversation with a friend, and you realize that all of the words, all of the concepts, the patterns of your speech, are all things that you got from somewhere else, they flow through you, from person to person, throughout history - you're not having a conversation, the conversation is having _you_
Or, you start thinking about your life and the world and you think about incredible pain you've experienced. And great beauty you've seen. And your greatest fear. And your greatest joy. And you realize - the palette of your experience has _incredible_ dynamic range, like your brain is some kind of magnificent radio and the music it plays is every perception you have - from colors and smells to the most complicated ideas are all things it can receive or transmit or something .... but who is listening?
Or any of thousands of other non-normal schemas. None of these function as scientific knowledge - they're shifts in perspective, but they don't make new predictions (or if they do, those predictions can be re-explaned back into the scientific materialist metaphor!).
And while the goal of science is to see reality as it really is, there's a default perspective to science, which is to isolate components to see how they work in a simplified context, and then to say "the complexity of reality is just like the simplicity of the simplified contexts, only without the simplification" which is a super interesting hallucination but I don't see why it's any more _correct_ than any of the other visions of complexity