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How do you get this number? Googling a bit, the D-T reaction produces 17.59 MeV per helium atom, so it should yield

17.59 MeV / (helium-4 atomic mass) = 0.117 TWh/kg

in thermal energy per kg of helium produced. The U.S. electricity production in 2019 was 4,118 TWh [1] and 4118 TWh / 0.117 (TWh/kg) = 35,196 kg.

If we assume some inefficency in the thermal->electricity conversion, I guess it should produce at least 70,000 kg/year.

I wonder if you could run the process energy negative to produce a lot of helium instead of energy ?

The answer should be clear from the quantities in the parent comment. No. Not economically viable at any plausible price.

Maybe we will start projects with enormous power requirements?