I haven't. But I suspect that's next. If you compare things like Lumo / Planck (ClojureScript) to Babashka (GraalVM-based Clojure), you can clearly see the perf benefits of going native.

This stuff is arguably just an initial foray into the embedded world. You could imagine a Clojure dialect or compiler that emits WASM, or C, or even native code.