PDF and TeX are broken beyond repair in terms of accessibility. The former because it allows the text and image to be split, and very few people care about text as long as it looks alright. And the latter because it's entire document representation model is based around computation. Knuth purposefully made it Turing complete in a misguided attempt at timelessness (no need for a replacement if it's infinitely extensible right?), which means there is no proper way to view a TeX document as "just text data".
I've worked in a library digitising documents, and whenever we encountered PDFs we'd just OCR the damn thing.
We need to throw the thing out, swallow the bitter pill of sub optimal kerning, and replace it with HTML asap.