Like a chrome extension that sends trackers lots of randomized user actions and garbled data instead of just blocking them? We'd make the data unreliable and render it useless! What an incredibly sly counter-attack.
I think it could take a fair amount of work to be effective (i.e. reverse engineering APIs, formatting payloads, etc) but I'm sure a community of engineers would support those efforts if it were in wide enough use. The problem here is that those engineers may be deterred by the possibility of getting sucked into legal battles. Maybe if it were backed by an organization that could allay that fear like the EFF, Mozilla or the FSF then I could see this actually having a shot of being genuinely effective.