A lot of businesses that could only survive on VC money have/will collapse, and the good businesses will stay good, albeit maybe with slower growth or smaller margins.
The large companies will power through, and maybe even hire up some of the really great talent that was at now-defunct startups.
Some new businesses will spring up to address our new realities.
The lockdown will end one way or another. Maybe some things will be forever different, like after 9/11. Maybe we'll have to wear masks in public forever. Sounds like a great opportunity for a fashion brand. Maybe we'll have to take our temperature to enter a public place forever. Sounds like an opportunity to make rapid temperature scanners that work on crowds.
In the grand scheme of things, this won't make a huge difference to the business cycle.
Some companies will die, others will be born.