Rather than thinking of space as empty vs non-empty, it might be better to think of space as a relationship between things.
I think you make less commitments of space this way.
I think you make less commitments of space this way.
But there are other trade-offs.
https://www.quantamagazine.org/coder-physicists-are-simulati...
But you might also think, “this eyebrow is hairs with not too much space between.”, or “this box is hydrogen and oxygen without too much space between.”
An eyebrow is hairs with a certain spatial density and distance (space) from the eyes. Water is hydrogen and oxygen with relatively less space between than say water vapor.
If I think of space as a magnitude, all the math and forces still work out, but there is “room” for other stuff.