For us techies, no, it doesn't really matter.
For average business owners who buy a WordPress template and some 5€ hosting in order to set up a business card web site on their own, on the other hand, it matters a lot. So if your project targets that group of people then PHP is pretty much the only option; anything more complicated than an FTP upload/MySQL import is pretty much to advanced for them and they generally aren't interested in learning new skills just to get a web site online.