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I'm using one as my work desktop and it's a very nice unit. It will not do Hyper-V for some reason but it'll run 4-6 VMWare instances just fine.

The double M2-SSD and double 2.5" SATA for RAID is also great in such a tiny box.

I really hope a new BIOS will make it compatible with the Ryzen 4000 desktop APUs when they arrive later this year.

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Would the Renoir desktop APUs make such a thing VR-ready? I'm looking for a cheap-enough box for working in the VR window manager Simula.

The available power budget and memory bandwidth will be the limiting factors for those new APU-s, just like for the current generation. Given the performance requirements that I have seen for VR I don't think the new APU-s will be able to reach that performance level.

For something less demanding it could be OK, not sure where your use case would fit in the performance requirement scale though.

LowSpecGamer did an experiment with VR and Ryzen APU-s, if you want to get an idea of what performance to expect: https://youtu.be/huT6fp7nzwA

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