Would highly recommend Tailwind if you don't like the boxed-in nature of most frameworks. Tailwind is more of a design system than a CSS framework. It simply gives you guidance on establishing proper constraints of your design system and then a nice set of utilities to get started with. There is no "can't be handled" scenario in Tailwind.

EDIT: And the book by the same author, Refactoring UI, is also a fantastic primer on the philosophy behind Tailwind.