I've had an iPad1, now have a rooted Nook Color, and on Friday (or Saturday) will be getting an iPad2.
The Nook Color is great in all ways except one: video. No Netflix client available or forthcoming, no streaming from NAS a la Air Video Server, and no VNC. No good hardware-assisted video players either, especially not for free.
Otherwise it's a great deal for $250 and works very well as a Kindle reader, web browser, e-mail client, etc., and as a good way to dip your toes into the Android tablet market.