One particular example that changed everything for me was the natural and simple way I could build the typical callback constructs with -> and => , so they almost look like blocks in ruby, and feel way more natural as a control construct, and I didnt have to stack lots of })}); and so on.
If you're rather new to something, the ease of use and the simplicity and readability speeden up the learning process extremely.
That being said, there are also a couple of things in cs that are kind of silly.. like using 'for i in my_array', but 'for k of my_dict', and stuff like that, that are really hard to debug.
Although, in terms of debugging, the fact that it gets compiled and possible errors are early detected and a canonical js is generated also saved me lot of time, in particular with IE ;-)