Please watch this video on the i3 desktop environment. The windows are managed and can be controlled by keystrokes.
https://www.youtube.com/watch?v=b_RL_Q8CR78
From 2015, a blind engineer uses emacspeak to write C++.
https://www.businessinsider.com/how-blind-google-engineer-wr...
I have read some HN comments in the past from blind engineers. Not sure if they are frontend.