Most consumer drives are still sold rated as <10^14 bits read per error. That's 12.5 terabytes, so in the worst case you could end up in situations where — on average — you are unable read a full 16TB drive without an error. Needless to say this is less than optimal for rebuilding a failed RAID array.
Anecdotal evidence (i.e. very low error rates during ZFS scrubs) suggests that manufacturers underrate their drives and they are much more reliable than that, but it is something to keep in mind.
Fortunately drive capacity completely outpaced my needs for personal data storage in the recent years, so I am happy with JBOD or RAID1, with backups of course.
[1]http://www.raidtips.com/raid5-ure.aspx [2]https://magj.github.io/raid-failure/