Imagine a treatment that would being people back to life. Surely if you saw that 11 times you would believe it worked. In fact, after n = 1, you would be so amazed you'd be thinking there is a trick. The point is that, while N is important, the N needed to uncover a signal differs wildly with the outcome you're trying to affect, specifically the outcome's variance. If one of these drug cocktails 'works' (which has many different definitions in clinical research), the signal may be obvious enough that n = 11 is enough to hone in on a promising treatment for further study. It's complicated.