Perhaps you should consider quality, not quantity.

I have been through a similar situation but have never sent out more than one resume at a time, ever. And every one was custom.

Whenever you find a prospective opportunity, learn everything you can about it. Try to get a personal introduction if you can. Write a cover letter and resume that specifically targets what they want, not what you want. Avoid headhunters (if you can) and follow up, follow up, follow up. Use any means you have to uncover opportunities (some call this "networking"). Better yet, get someone to create a position for you. (I know this is tough, but so what.)

I see entry level positions all the time. Be prepared to move if you have to. Take the waiter job and then plug away for an IT job in your spare time. I know there's something out there for you, persevere and find it.