In theory. But in practice, as a developer you don't want to depend on the browser support for your whole product. Conferencing features of browsers have been pretty lame, compared to what's possible in a professional product.

{edit} My experience: investor took over our startup, made us switch from bespoke technology to web-based conference features. Every feature was compromised, reliability and capacity reduced by 10X.

Based on my experience with Zoom on the one hand and that Google thing on the other, yes, yes it does.

Browser blocking and plugin features can prevent it from working. For example, I’ve been in hangouts meetings where the video feed wouldn’t load because autoplay was blocked on the browser. Of course, you can work around that, but having the Zoom desktop client provides a reliable experience without any tweaking

For better or for worse, WebRTC is very opinionated about codecs and transports. Those might be great choices for some scenarios, but no developer wants their whole business to be constrained it.