If you can share a view details on your setup that would be great!
On the mac, Version 3.4.3 is working fine with Catalina (10.15.4).
It adds in a virtual camera interface and you can configure a pipeline of sources or pipelines.
An easy setup is: - Webcam (set to FaceTime HD Camera) - Matrix effect
A more complex one is: - Add webcam - Select "movie" but press PIP - In the PIP Movie settings, "Swap with Video Source" - Mess with the Chroma key settings (you need a solid background color) for Chroma to work. I use a bed sheet :)
I'll circle back with the OBS/Syphon Pipeline/CamTwist shortly as it was much more involved!