- Chinese doctors initially tested chloroquine in-vitro on SARS-Cov-2 and it reduced the viral load significantly. Similar results were observed with other viruses including SARS-Cov.
- They then tested it in-vivo (on patients) and it showed promising results
- The speaker explains then that they had 3 cohorts of infected patients on which they tested daily for SARS-Cov-2. First cohort was the control (no treatment), second one received Plaquenil (hydroxychloroquine), third one received Plaquenil and azithromycin (an antibiotic). After 7 days 1st cohort had approximately 85% testing positive, 2nd 40%, 3rd 5%. One could be surprised by the use of an antibiotic but it apparently helps with fight opportunistic bacterial infection resulting from a viral pneumonia. He adds that for every recorded death, the patient tested positive for the virus before their death and concludes that if the double treatment of azythromicin + Plaquenil reduces the viral load, then it would improve patient prognosis.
In conclusion, I think it's quite a big deal if it is confirmed that chloroquine can reduce contagiosity and improve outcomes. It's widely available, cheap and safe. Give it to everyone showing symptoms, individuals who were in contact with confirmed cases, medical professionals, and you'll surely reduce R0 significantly.
video: https://www.youtube.com/watch?v=n4J8kydOvbc&feature=emb_titl...
pre-pub paper: https://www.sciencedirect.com/science/article/pii/S092485792...
ppt (last page is result of experiment mentioned above): https://www.mediterranee-infection.com/wp-content/uploads/20...