Being a libertarian doesn't conflict with wanting to be forward looking, or with wanting to do ambitious projects. And a "small 'l' libertarian" might even be OK with the State managing the construction of something like the Interstate highway system. A "Big 'L' Libertarian" would oppose funding such a project through coercive, involuntary taxation, but wouldn't necessarily oppose the idea in itself. They would just argue that a means of funding should be found that doesn't involve coercion.

That said, I don't know Peter Thiel and I don't know how deeply his libertarian roots run, or how much of an ideologue he is. There are a lot of people who call themselves libertarians that I wouldn't necessarily call libertarians myself. <shrug />