Not only that, by using this you will increase your S3 bill, by definition of how this works.
If you are going to use windows explorer and enter a directory full of images — windows explorer will fetch thumbnail for _every_ image. If you have 50000 files there, that's 50000 requests + bandwidth for 50000 files.
Same for video or audio. Getting metadata isn't free.
But the worst case scenario if you have a big big file, let's say vhdx disk image, that you mount and keep modifying every minute.
S3 protocol doesn't have 'modify', it will _have_ to reupload entire file every time even if a single byte is changed. For a 10G file changed 1000 times that's 10 terabytes of traffic.