I do not know this as a fact, but I don't believe US pharmacists are able to adjust dosing on the fly - though of course they can and do reach back out to physicians with questions.
I had an experience recently that really solidified my respect and appreciation for pharmacists though. I was standing in line behind a older gentleman who had maybe a 10 minute conversation with the pharmacist. I tried to mind my own business but couldn't help but hear the overall gist. He was very confused about what his medication was for and especially how to take it. The pharmacist clearly had a relationship with him and wrote down schedule based on the meds he was already taking. He thanked her by name and she told him she's give him a call later in the week to check in on how he was managing.
I was curious (and the last person in line) so I asked her about her work and how often she ends up so involved. Apparently she made lots of calls throughout the week to people, and people came in confused about their medications often enough. By percentage it sounded like a minority of the patients, but her assistance was obviously super important to a lot of people in the neighborhood.
I don't think I've ever asked a pharmacist for more info on my life, but I'm very grateful they exist as a resource. At the very least, I think it's important we don't think of pharmacies as counting factories that can be replaced by robots. And while I'm all for dropping the price of healthcare across the board, I hope the kind of value that kind of one-on-one interaction at least gets it's fair shake in any accounting done thinking about making a switch to tele-pharmacies and the like.
He advised to take it after food, which is true for any old pain killer (for example Ibuprofen), but not for such specific medications.
In fact it should be taken half an hour before a meal.
That's the reason why it's prescription only and deployed by a pharmacist, who immideately caught it an gave me correct advice.
Isn't that written down in the manufacturer's datasheet that comes with the drugs when you get the rx filled?
But usually doctors are very busy people, who may look it up in the compendium, but don't necessarily have time to dig into the details.
I don't fault him and that's exactly where the pharmacist comes in.
It used to be all 4 at Walmart, and then something utterly ridiculous happened. For the non-US readers who won't believe this idiocy, I swear it is true. We really do put up with this nonsense.
One of them was for irbesartan. I'm supposed to take it twice a day, 150 mg each time. The prescription was written for 30 x 300 mg tablets, which I split in two (irbesartan comes in a rod shaped tablet that you can easily split it two by hand).
This is $9 cash at Walmart.
But then there were some irbesartan recalls (although not affecting the manufacturer of any tablets I had). There was a shortage of 300 mg tablets, and Walmart was having trouble refilling my prescription.
So we had my doctor change it to from 30 x 300 mg tablets to 60 x 150 mg tablets. The cash price for 30 x 150 mg is $9 at Walmart, same as 30 x 300 mg. (I'd guess that for this drug, most of the cost is in filler and binder, so that is probably not unreasonable). So I'd expect 60 x 150 mg to be $18.
Walmart filled that, and when I went to pick it up...it was something like $300. WTF!? So they double checked, and found out that it had actually been written as 180 x 150 mg. They redid it as 60 x 150 mg, which dropped the price to about $100. So, still a big WTF.
According to GoodRx it should be $24 cash (still a WTF...why not $18?). Since this is one that GoodRx thinks has a good cash price at Walmart, GoodRx does not offer a coupon for it there. I showed the pharmacist the listing in the GoodRx app, and he agreed to honor that price, so I got my prescription for $24.
GoodRx did have a coupon for Safeway, for 60 x 150 mg for around $13, so when it was time to re-fill that, I move it there. (That changed to about $18 next month).
I ran out of re-fills about 3 months later and so needed a new prescription, and by then 300 mg was readily available again so asked for 90 x 300 mg, which was $21 with a GoodRx coupon at Safeway.