During my worst commute I was spending 4.5 hours traveling to and from work each day. A long day at work meant doing nothing but work, travel, and sleep and still being deprived of sleep. I didn't last six months, and I have no family or anyone to depend on me.

When I worked from home I lived in a difficult climate which became overly pleasant. The worst snow storm didn't bother me in the slightest, if I didn't feel like going outside I just didn't. When bearing the cold became optional, it was a pleasant luxury going outside instead of a chore.

The human interaction you are talking about is real, but so is losing a large chunk of your life getting to work.