I recommend using mpv with the open-with extension instead (right click -> open with -> mpv.) Thanks to youtube-dl, mpv will handle most any video website except netflix. If you tell mpv to stay-on-top, the effect essentially picture-in-picture, but with the full capability of mpv. You can drag new links into mpv to change what video is playing (hold down shift while dragging in a new link to append to the playlist.)