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In the 80s in order to prove that ulcers were caused by bacteria, a doctor infected himself with said ulcer-causing bacteria and treated himself with antibiotics.

https://www.discovermagazine.com/health/the-doctor-who-drank...

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In the 19th century, in order to prove that "dirtyness" causes cholera, a man named Pettenkofer drank a vial of clear water contaminated with cholera. Fortunately he attempted to control the experiment by neutralizing his stomach acids beforehand, which prevented the cholera from becoming pathogenic. The colony passed through his digestive tract without incident.

He neutralised his stomach acids to keep the V. cholerae alive, actually.

They didn't pass through him without incident, every account of this story I can find notes that he did get sick. The modern perspective of the story seems to be that he had an immunity from previously having dealt with cholera.

The story I heard was that Cholera automatically stops reproducing if its population gets high enough, and that keeping the cholera alive prevented it from spreading.

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