The one I'm terrified of is the switch where the laws of physics all change at the speed of light. We will simply cease to exist and not even see it coming.
The real danger would be a super but unintelligent race doing the same (think "giant space ants"), since they wouldn't have philosophy department chairs.
The exception would be the fanatically oriented, as acting in opposition to logic is part of the basic premise.
Can't quite make myself claim it's better than Orthogonal.