In the world of ebooks, indies actually have the upper hand. For one, we don't have the overhead of big publishers, so we can sell ebooks at more reasonable prices (while pocketing more than authors with traditional contracts). We have the ability to move more quickly and thus take advantage of new features (like Amazon's ad platform) earlier. We can sell worldwide with a click, instead of negotiating messy contracts.
With print on demand, we can also have our books in print. But publishers definitely have the upper hand there and, I presume, always will.
Also, as an indie I have the option to make my books available DRM-free.
Personally, I _like_ ebooks, especially for fiction. They weigh nothing. They have search. My highlights can get aggregated together. I can switch devices and even switch between ebook and audiobook. Further, I think there are very few print books that actually have real resale value, so that's not a big factor for me.