Smallpox - eradicated from the face of the earth (barring lab samples).
Polio - only 50 years ago, there were tens of thousands of cases in the U.S. Ten years later, after a serious vaccination push, it was down to a bit over a hundred cases. 1979 - last indigenous Polio transmission in the U.S. (globally, it just won't die, in large part thanks to the efforts of religious fruit-loops convincing people it's a plot by the U.S. to sterilise them; we pushed it more or less down to a single country, and now heart-breakingly it's spreading from there again).
Whooping cough - beaten down from tens of thousands of deaths to dozens in the U.S., and then cases started rising again when people stopped having their children vaccinated at the start of the 21st century.
The list of diseases that no longer present a real daily threat to people goes on and on. Let's have someone big from the relevant government agency on the news telling people that they're killing children by dodging vaccinations.