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Comment by Geimfari | Hacker News Reader

Your first source is a bad one but here is a review: [1] The association is really not strong but the authors do advice against indiscriminate paracetamol use.

[1] https://www.ncbi.nlm.nih.gov/pubmed/29341895 [2] https://www.ncbi.nlm.nih.gov/pubmed/26930528

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Tylenol/paracetamol use should be sparing to begin with just because of its harsh effect on the liver.

While the liver toxicity alone would seem to argue against indiscriminate acetaminophen (google tells me that is the same as "paracetamol" but that is a new name to me) use, I would expect common sense to argue against indiscriminate use of anything that is not simply food. I'd look to evidence like you provide to advise me as to how, exactly, I should discriminate. But indiscriminate use of most things seems inadvisable.

Is there any alternatives suggested for this medicine?

Naproxen is far, far better for pain, and doesn't have anywhere near the possibility of cooking your liver.

Umm NSAIDs like Naproxen have their own list of issues which may be worse than Tylenol. Another issue is that Tylenol is often used because it does not interact with other NSAIDs so if you are not sure if someone has taken medication with a NSAID in it, you can safely give them Tylenol, generally speaking, where as if you give them more NSAIDs you could potentially risk an overdose. So its not as simple as Napoxen is superior to Tylenol. IANAD,

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