For example, it is impossible in general to understand what an English sentence says, because that sentence may describe the operation of an arbitrary program, and understanding an arbitrary program is undecidable.
Another example, it is impossible to detect all variants of malicious programs, because that requires understanding what all programs do, which requires identifying whether an arbitrary program halts or not.
Yet another example, optimal machine learning is impossible, since that is based on Solomonoff induction, based on Kolmogorov complexity, which is uncomputable due to the halting problem.
And another off the top of my head, it is impossible to create a general program creating program, such that you give it a well defined specification and it spits out a program that meets the requirements, if the requirements are satisfiable, since that requires solving the halting problem.
Finally, humans, while not optimally satisfying all the above tasks, do quite a decent job at these tasks, which is surprising if humans themselves were some sort of algorithm. So, this strongly suggests the human mind is doing some operation beyond computation, which in turn would imply that human intelligence level AI is impossible in theory, and thus impossible in practice. Furthermore, if the human mind is indeed doing something uncomputable, this has technological implications that human in the loop computation approaches are inherently more powerful than computation alone, a vastly under researched concept, although arguably the secret to the success of most AI/ML/datamining companies these days, such as Google, Facebook, Amazon, and Palantir. And the software industry in general is proof of this concept that humans are program generating processes performing much better than the halting problem would lead one to expect if humans were indeed mere computation.
Anyways, a whole bunch of impossibility implications, which have the practical application of protecting your wallet from comp. sci. snake oil salesmen, and the intriguing possibility 'beyond computation' technology.