I agree with your point in general, but surely the fact that there are 10 million js frameworks invented every week is proof that the native DOM APIs are not a good abstraction? As a mostly front end dev, most of my UI logic these days target _React_, not the dom APIs. To the extent that I write JavaScript, it’s pure data manipulation, which can be written in any language.
In other words, the particulars of the language matters. I wouldn't underestimate 20+ years of JS evolution toward expressing the problem better.
I'm working on my own language and all those details are hard. When they work, they're invisible to users. You only notice when it's not there or doesn't work! I would agree that Python is a better language than JS in most respects, but it's not clear to me that it's a better language for writing web front ends.
e.g. the async abstractions and promises are different and I believe that matters.