Originally my conception of the video was more like this commenter below: It’s been a while since I’ve watched the video but its more about JavaScript becoming the universal assembly language.
I guess a lot of people are saying "he predicted this" without referring what specifically he is predicting.
FWIW it's not clear to me that WASM is going to do that. Everything I've heard from the team says that WASM and JS are complementary. Not that WASM will cause JavaScript to die.
I think there's some possibility of that happening in the distant future, but it's far from obvious. I think JS VMs will always be better at running JS than WASM VMs running JS engines, and all the JS out there will exist for a long time.
Also, JS is at a pretty good level of abstraction to manipulate the DOM, whereas C, C++ and Rust aren't. And it has some good syntactic shortcuts. Despite being a Python person, I would probably even argue that JS is better to manipulate the DOM, despite JS and Python being very similar otherwise. Function literals might be one reason.
So when people say "he predicted this", it would be nice to be specific about what the prediction was. WASM is a step in that direction but I would argue it's also fairly clear given that asm.js existed and he showed it. The real question is if WASM can handle all these use cases. Working on a language has made me appreciate many reasons that it's hard to make a polyglot VM. Tiny changes can bias your VM towards one compilation source vs. another.