I recently decided to do a round of interviews after 10+ years as an independent web / iOS dev, having never had a professional software dev job. I'm also a self-taught developer with a business degree from a no-name state school. Despite all that, I've been really surprised and happy with the market reception here in NYC. I got interest from the bigger guys like Amazon, FB, and Twitter, as well as smaller companies like Dropbox, Stripe, Square, Coinbase, etc. Last week, I got a very good senior / staff offer from one of the smaller public companies for around $400k in first year comp. With bonuses, promotions, refreshers, etc, that could easily average $500k - 600k per year over the next few years. And I had no competing offers. Some of the other companies I'm in the loop with will almost certainly offer quite a bit more, although I love this company that made the offer and I'll probably just drop the other interviews and take it. Comp isn't everything.
All this to say, if you're interested in making more $$ and these companies are hiring where you live, don't pass it up because you think it's only for hotshot 22-year-olds coming out of Stanford.