Is that what “high speed digital design” is? Like the stuff that Dr Howard Johnson teaches? Or is that not the same scope or maybe still something entirely different?
https://hackaday.com/2019/01/24/video-putting-high-speed-pcb...
Dont remember the exact video, but Bill Herd mentioned many times about on site last minute fab fixes involving prodding the product on a hunch of where the problem might be.
Today you can simulate and measure pretty much everything, plus automated design rule tools will warn you of potential problems beforehand.