Is that a skill that's related to how you do optimisation in certain puzzle games? E.g. TIS-100, Opus Magnum, Factorio. Or not really?
The big breakthroughs were the ability to simulate hardware for larger circuits at higher frequencies realistically to determine how to make those circuits stable rather than to get them to oscillate wildly at the frequencies they operate at. Once you develop a bit of appreciation for what is required to make a 100 gates work reliably at 10 MHz or so you can begin to understand the black magic required to make billions of transistors work reliably at frequencies in the GHz.
So the skill is not at all related to puzzle games, but it is a puzzle and the tools and knowledge required were usually hard won. At those frequencies and part sizes anything is an antenna, there is no such thing as a proper isolator, coils, resistors and capacitors all over the place even if you did not design them into the circuit (parasitics).
If this sort of stuff interests you I highly recommend the 'Spice' tutorials, and/or to get an oscilloscope and some analog parts to play with.
https://hackaday.com/2019/01/24/video-putting-high-speed-pcb...
Dont remember the exact video, but Bill Herd mentioned many times about on site last minute fab fixes involving prodding the product on a hunch of where the problem might be.
Today you can simulate and measure pretty much everything, plus automated design rule tools will warn you of potential problems beforehand.