After switching to wireguard I've been really blown away at how much better the experience is on a phone than other VPN methods. It's always on on my phone as long as I'm not using my home wifi, and I just never need to think about it.
Thanks.
Edit: I'm talking about the iOS version, not sure what platform you're using.
However, there are other Android apps that implement Wireguard that do expose their intents. I use Viscerion with Tasker quite happily.
Personally I have the luxury of running the VPN server at home, so I can just always leave it on.